Treatment of Fistulizing Perianal Crohn's Disease by Autologous Microfat Enriched With Adipose-Derived Regenerative Cells

Karam Matlub Sørensen; Charlotte Harken Jensen; Søren Paludan Sheikh; Niels Qvist; Jens Ahm Sørensen

doi:10.1093/ibd/izab276

Treatment of Fistulizing Perianal Crohn's Disease by Autologous Microfat Enriched With Adipose-Derived Regenerative Cells

Karam Matlub Sørensen^*, Charlotte Harken Jensen, Søren Paludan Sheikh, Niels Qvist, Jens Ahm Sørensen

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Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Abstract

In this pilot study, short-term efficacy and safety of fat graft enriched with Adipose-Derived Regenerative Cells (ADRC) in the treatment of Crohn's high anal fistula was evaluated. Clinical fistula healing was achievable in 75% of cases, by a single treatment.

Originalsprog	Engelsk
Tidsskrift	Inflammatory Bowel Diseases
Vol/bind	28
Udgave nummer	6
Sider (fra-til)	967-970
ISSN	1078-0998
DOI	https://doi.org/10.1093/ibd/izab276
Status	Udgivet - 3. jun. 2022

Dokumenter og links

10.1093/ibd/izab276

1 Ph.d.-afhandling

Minimal invasive approach in the management of perianal suppuration disease
Sørensen, K. M., 1. nov. 2021, Syddansk Universitet. Det Sundhedsvidenskabelige Fakultet. 78 s.
Publikation: Afhandling › Ph.d.-afhandling

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Citationsformater

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title = "Treatment of Fistulizing Perianal Crohn's Disease by Autologous Microfat Enriched With Adipose-Derived Regenerative Cells",

abstract = "In this pilot study, short-term efficacy and safety of fat graft enriched with Adipose-Derived Regenerative Cells (ADRC) in the treatment of Crohn's high anal fistula was evaluated. Clinical fistula healing was achievable in 75% of cases, by a single treatment.",

keywords = "Crohn{\textquoteright}s disease, cell therapy, rectal fistula, stem cells, Humans, Crohn Disease/complications, Transplantation, Autologous, Treatment Outcome, Rectal Fistula/etiology, Mesenchymal Stem Cell Transplantation",

author = "S{\o}rensen, {Karam Matlub} and Jensen, {Charlotte Harken} and Sheikh, {S{\o}ren Paludan} and Niels Qvist and S{\o}rensen, {Jens Ahm}",

year = "2022",

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doi = "10.1093/ibd/izab276",

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T1 - Treatment of Fistulizing Perianal Crohn's Disease by Autologous Microfat Enriched With Adipose-Derived Regenerative Cells

AU - Sørensen, Karam Matlub

AU - Jensen, Charlotte Harken

AU - Sheikh, Søren Paludan

AU - Qvist, Niels

AU - Sørensen, Jens Ahm

PY - 2022/6/3

Y1 - 2022/6/3

N2 - In this pilot study, short-term efficacy and safety of fat graft enriched with Adipose-Derived Regenerative Cells (ADRC) in the treatment of Crohn's high anal fistula was evaluated. Clinical fistula healing was achievable in 75% of cases, by a single treatment.

AB - In this pilot study, short-term efficacy and safety of fat graft enriched with Adipose-Derived Regenerative Cells (ADRC) in the treatment of Crohn's high anal fistula was evaluated. Clinical fistula healing was achievable in 75% of cases, by a single treatment.

KW - Crohn’s disease

KW - cell therapy

KW - rectal fistula

KW - stem cells

KW - Humans

KW - Crohn Disease/complications

KW - Transplantation, Autologous

KW - Treatment Outcome

KW - Rectal Fistula/etiology

KW - Mesenchymal Stem Cell Transplantation

U2 - 10.1093/ibd/izab276

DO - 10.1093/ibd/izab276

M3 - Journal article

C2 - 34791256

SN - 1078-0998

VL - 28

SP - 967

EP - 970

JO - Inflammatory Bowel Diseases

JF - Inflammatory Bowel Diseases

IS - 6

ER -

Treatment of Fistulizing Perianal Crohn's Disease by Autologous Microfat Enriched With Adipose-Derived Regenerative Cells

Abstract

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Minimal invasive approach in the management of perianal suppuration disease

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