TY - JOUR
T1 - The Effectiveness of a Very Low-Volume Compared to High-Volume Laxative in Colon Capsule Endoscopy
AU - Schelde-Olesen, Benedicte
AU - Nemeth, Artur
AU - Johansson, Gabriele Wurm
AU - Deding, Ulrik
AU - Bjørsum-Meyer, Thomas
AU - Thorlacius, Henrik
AU - Baatrup, Gunnar
AU - Koulaouzidis, Anastasios
AU - Toth, Ervin
N1 - Publisher Copyright:
© 2022 by the authors.
PY - 2023/1
Y1 - 2023/1
N2 - Colon capsule endoscopy (CCE) is a promising modality for colonic investigations, but completion rates (CR) and adequate cleansing rates (ACR) must be improved to meet established standards for optical colonoscopy. Improvements should be made with patient acceptability in mind. We aimed to compare a very low-volume polyethylene glycol (PEG) laxative to a conventional high-volume laxative. We carried out a single-center retrospective comparative cohort study including patients referred for CCE. One hundred and sixty-six patients were included in the final analysis, with eighty-three patients in each group. We found a CR and ACR of 77% and 67% in the high-volume group and 72% and 75% in the very low-volume group, respectively. In the high-volume group, 54% had complete transit and adequate cleansing, whereas this was the case for 63% in the very low-volume group. No statistically significant difference in CR, ACR, or a combination of the two was found. A very low-volume bowel preparation regimen was non-inferior to a high-volume regimen before CCE in terms of CR and ACR.
AB - Colon capsule endoscopy (CCE) is a promising modality for colonic investigations, but completion rates (CR) and adequate cleansing rates (ACR) must be improved to meet established standards for optical colonoscopy. Improvements should be made with patient acceptability in mind. We aimed to compare a very low-volume polyethylene glycol (PEG) laxative to a conventional high-volume laxative. We carried out a single-center retrospective comparative cohort study including patients referred for CCE. One hundred and sixty-six patients were included in the final analysis, with eighty-three patients in each group. We found a CR and ACR of 77% and 67% in the high-volume group and 72% and 75% in the very low-volume group, respectively. In the high-volume group, 54% had complete transit and adequate cleansing, whereas this was the case for 63% in the very low-volume group. No statistically significant difference in CR, ACR, or a combination of the two was found. A very low-volume bowel preparation regimen was non-inferior to a high-volume regimen before CCE in terms of CR and ACR.
KW - bowel cleansing quality
KW - bowel preparation
KW - capsule endoscopy
KW - completion rate
U2 - 10.3390/diagnostics13010018
DO - 10.3390/diagnostics13010018
M3 - Journal article
C2 - 36611310
AN - SCOPUS:85145841711
SN - 2075-4418
VL - 13
JO - Diagnostics
JF - Diagnostics
IS - 1
M1 - 18
ER -