Reference Ranges in [(99m)Tc]Mercaptoacetyltriglycerine Renography: Comparison of a Semi-automated (Xeleris, GE) and Manual (Picker, Odyssey) Processing Software

Kate I Rewers; Svend Hvidsten; Oke Gerke; Søren Schifter

doi:10.1007/s11307-014-0813-5

Reference Ranges in [(99m)Tc]Mercaptoacetyltriglycerine Renography: Comparison of a Semi-automated (Xeleris, GE) and Manual (Picker, Odyssey) Processing Software

Kate I Rewers, Svend Hvidsten, Oke Gerke, Søren Schifter

KI, OUH, Research unit of Clinical Physiology and Nuclear Medicine (Odense)

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

PURPOSE: The purpose of the study was to define reference ranges for quantitative parameters in [(99m)Tc]mercaptoacetyltriglycerine ([(99m)Tc]MAG3) renography to assist interpretation in a semi-automated (Xeleris, GE) compared to a manual (Picker, Odyssey) software package.

PROCEDURES: Forty-eight subjects approved for renal donation were evaluated with [(99m)Tc]MAG3 renography using both the Xeleris and the Picker software.

RESULTS: Reference ranges for the two software were comparable regarding the relative function of the two kidneys (the split function, SF) and the residual activities (RA). The time to peak whole-kidney activities (T max whole-kidney) was more dependent on the type of software. Using Bland-Altman limits, we found good and acceptable agreement between the two methods.

CONCLUSIONS: We found good correlation between renography results using the Xeleris and Picker software packages. However, software-specific reference ranges are needed.

Original language	English
Journal	Molecular Imaging and Biology
Volume	17
Issue number	5
Pages (from-to)	620-624
ISSN	1536-1632
DOIs	https://doi.org/10.1007/s11307-014-0813-5
Publication status	Published - Oct 2015

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10.1007/s11307-014-0813-5

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@article{dd0610f68f434d11b67476fd04d405fc,

title = "Reference Ranges in [(99m)Tc]Mercaptoacetyltriglycerine Renography: Comparison of a Semi-automated (Xeleris, GE) and Manual (Picker, Odyssey) Processing Software",

abstract = "PURPOSE: The purpose of the study was to define reference ranges for quantitative parameters in [(99m)Tc]mercaptoacetyltriglycerine ([(99m)Tc]MAG3) renography to assist interpretation in a semi-automated (Xeleris, GE) compared to a manual (Picker, Odyssey) software package.PROCEDURES: Forty-eight subjects approved for renal donation were evaluated with [(99m)Tc]MAG3 renography using both the Xeleris and the Picker software.RESULTS: Reference ranges for the two software were comparable regarding the relative function of the two kidneys (the split function, SF) and the residual activities (RA). The time to peak whole-kidney activities (T max whole-kidney) was more dependent on the type of software. Using Bland-Altman limits, we found good and acceptable agreement between the two methods.CONCLUSIONS: We found good correlation between renography results using the Xeleris and Picker software packages. However, software-specific reference ranges are needed.",

author = "Rewers, {Kate I} and Svend Hvidsten and Oke Gerke and S{\o}ren Schifter",

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Reference Ranges in [(99m)Tc]Mercaptoacetyltriglycerine Renography: Comparison of a Semi-automated (Xeleris, GE) and Manual (Picker, Odyssey) Processing Software. / Rewers, Kate I ; Hvidsten, Svend ; Gerke, Oke et al.
In: Molecular Imaging and Biology, Vol. 17, No. 5, 10.2015, p. 620-624.

Research output: Contribution to journal › Journal article › Research › peer-review

TY - JOUR

T1 - Reference Ranges in [(99m)Tc]Mercaptoacetyltriglycerine Renography

T2 - Comparison of a Semi-automated (Xeleris, GE) and Manual (Picker, Odyssey) Processing Software

AU - Rewers, Kate I

AU - Hvidsten, Svend

AU - Gerke, Oke

AU - Schifter, Søren

PY - 2015/10

Y1 - 2015/10

N2 - PURPOSE: The purpose of the study was to define reference ranges for quantitative parameters in [(99m)Tc]mercaptoacetyltriglycerine ([(99m)Tc]MAG3) renography to assist interpretation in a semi-automated (Xeleris, GE) compared to a manual (Picker, Odyssey) software package.PROCEDURES: Forty-eight subjects approved for renal donation were evaluated with [(99m)Tc]MAG3 renography using both the Xeleris and the Picker software.RESULTS: Reference ranges for the two software were comparable regarding the relative function of the two kidneys (the split function, SF) and the residual activities (RA). The time to peak whole-kidney activities (T max whole-kidney) was more dependent on the type of software. Using Bland-Altman limits, we found good and acceptable agreement between the two methods.CONCLUSIONS: We found good correlation between renography results using the Xeleris and Picker software packages. However, software-specific reference ranges are needed.

AB - PURPOSE: The purpose of the study was to define reference ranges for quantitative parameters in [(99m)Tc]mercaptoacetyltriglycerine ([(99m)Tc]MAG3) renography to assist interpretation in a semi-automated (Xeleris, GE) compared to a manual (Picker, Odyssey) software package.PROCEDURES: Forty-eight subjects approved for renal donation were evaluated with [(99m)Tc]MAG3 renography using both the Xeleris and the Picker software.RESULTS: Reference ranges for the two software were comparable regarding the relative function of the two kidneys (the split function, SF) and the residual activities (RA). The time to peak whole-kidney activities (T max whole-kidney) was more dependent on the type of software. Using Bland-Altman limits, we found good and acceptable agreement between the two methods.CONCLUSIONS: We found good correlation between renography results using the Xeleris and Picker software packages. However, software-specific reference ranges are needed.

U2 - 10.1007/s11307-014-0813-5

DO - 10.1007/s11307-014-0813-5

M3 - Journal article

C2 - 25693723

SN - 1536-1632

VL - 17

SP - 620

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JO - Molecular Imaging and Biology

JF - Molecular Imaging and Biology

IS - 5

ER -

Reference Ranges in [(99m)Tc]Mercaptoacetyltriglycerine Renography: Comparison of a Semi-automated (Xeleris, GE) and Manual (Picker, Odyssey) Processing Software

Abstract

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