MMP mediated type V collagen degradation (C5M) is elevated in ankylosing spondylitis

S S Veidal; D V Larsen; Xijuan Chen; S Sun; Qiuju Zheng; Anne-Christine Bay Jensen; Diana Julie Leeming; A Nawrocki; Martin Røssel Larsen; G Schett; M A Karsdal

doi:10.1016/j.clinbiochem.2012.02.007

MMP mediated type V collagen degradation (C5M) is elevated in ankylosing spondylitis

S S Veidal, D V Larsen, Xijuan Chen, S Sun, Qiuju Zheng, Anne-Christine Bay Jensen, Diana Julie Leeming, A Nawrocki, Martin Røssel Larsen, G Schett, M A Karsdal

Department of Biochemistry and Molecular Biology

Nordic Bioscience

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Type V collagen has been demonstrated to control fibril formation. The aim of this study was to develop an ELISA capable of detecting a fragment of type V collagen generated by MMP-2/9 and to evaluate the assay as biomarker for ankylosing spondylitis (AS).

Original language	English
Journal	Clinical Biochemistry
Volume	45
Issue number	7-8
Pages (from-to)	541-6
Number of pages	6
ISSN	0009-9120
DOIs	https://doi.org/10.1016/j.clinbiochem.2012.02.007
Publication status	Published - 2012

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10.1016/j.clinbiochem.2012.02.007

Cite this

@article{f132306a8fe447cfb982db06156c261a,

title = "MMP mediated type V collagen degradation (C5M) is elevated in ankylosing spondylitis",

abstract = "Type V collagen has been demonstrated to control fibril formation. The aim of this study was to develop an ELISA capable of detecting a fragment of type V collagen generated by MMP-2/9 and to evaluate the assay as biomarker for ankylosing spondylitis (AS).",

author = "Veidal, {S S} and Larsen, {D V} and Xijuan Chen and S Sun and Qiuju Zheng and Jensen, {Anne-Christine Bay} and Leeming, {Diana Julie} and A Nawrocki and Larsen, {Martin R{\o}ssel} and G Schett and Karsdal, {M A}",

year = "2012",

doi = "10.1016/j.clinbiochem.2012.02.007",

language = "English",

volume = "45",

pages = "541--6",

journal = "Clinical Biochemistry",

issn = "0009-9120",

publisher = "Elsevier",

number = "7-8",

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TY - JOUR

T1 - MMP mediated type V collagen degradation (C5M) is elevated in ankylosing spondylitis

AU - Veidal, S S

AU - Larsen, D V

AU - Chen, Xijuan

AU - Sun, S

AU - Zheng, Qiuju

AU - Jensen, Anne-Christine Bay

AU - Leeming, Diana Julie

AU - Nawrocki, A

AU - Larsen, Martin Røssel

AU - Schett, G

AU - Karsdal, M A

PY - 2012

Y1 - 2012

N2 - Type V collagen has been demonstrated to control fibril formation. The aim of this study was to develop an ELISA capable of detecting a fragment of type V collagen generated by MMP-2/9 and to evaluate the assay as biomarker for ankylosing spondylitis (AS).

AB - Type V collagen has been demonstrated to control fibril formation. The aim of this study was to develop an ELISA capable of detecting a fragment of type V collagen generated by MMP-2/9 and to evaluate the assay as biomarker for ankylosing spondylitis (AS).

U2 - 10.1016/j.clinbiochem.2012.02.007

DO - 10.1016/j.clinbiochem.2012.02.007

M3 - Journal article

C2 - 22382088

SN - 0009-9120

VL - 45

SP - 541

EP - 546

JO - Clinical Biochemistry

JF - Clinical Biochemistry

IS - 7-8

ER -

MMP mediated type V collagen degradation (C5M) is elevated in ankylosing spondylitis

Abstract

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