TY - JOUR
T1 - Investigation of an Enterobacter hormaechei OXA-436 carbapenemase outbreak
T2 - when everything goes down the drain
AU - Raun-Petersen, Christina
AU - Toft, Annette
AU - Nordestgaard, Mette Marie
AU - Holm, Anette
AU - Overballe-Petersen, Søren
AU - Hammerum, Anette M.
AU - Hasman, Henrik
AU - Justesen, Ulrik Stenz
N1 - Publisher Copyright:
© 2022 The Authors
PY - 2022/9
Y1 - 2022/9
N2 - Over a time period of 18 months an Enterobacter hormaechei sequence type (ST) 90, harboring a blaOXA-436 carbapenemase gene, was isolated from seven patients at Odense University Hospital, Denmark. The patients were all from the same department, but there was no apparent direct epidemiological link. Whole genome sequencing (WGS) was performed on all clinical isolates as well as on a number of environmental samples including two E. hormaechei ST90 isolates carrying the blaOXA-436 gene, which were isolated in samples from two shower drains at the department. These drains were suspected to be the source of the outbreak.
AB - Over a time period of 18 months an Enterobacter hormaechei sequence type (ST) 90, harboring a blaOXA-436 carbapenemase gene, was isolated from seven patients at Odense University Hospital, Denmark. The patients were all from the same department, but there was no apparent direct epidemiological link. Whole genome sequencing (WGS) was performed on all clinical isolates as well as on a number of environmental samples including two E. hormaechei ST90 isolates carrying the blaOXA-436 gene, which were isolated in samples from two shower drains at the department. These drains were suspected to be the source of the outbreak.
KW - Carbapenemase producing organisms
KW - Enterobacter hormaechei
KW - Environmental transmission
KW - Whole genome sequencing
U2 - 10.1016/j.infpip.2022.100228
DO - 10.1016/j.infpip.2022.100228
M3 - Journal article
C2 - 35860606
AN - SCOPUS:85134316718
SN - 2590-0889
VL - 4
JO - Infection Prevention in Practice
JF - Infection Prevention in Practice
IS - 3
M1 - 100228
ER -